9) Siryn
Deadpool has had a few love interests over the years, though no doubt one of the best is Siryn. The daughter of Banshee (who you may remember from X-Men: First Class), she has a sonic scream and is an incredibly powerful mutant.
Siryn met Wade Wilson during a battle with Black Tom Cassidy and the Juggernaut, and he quickly became infatuated with her, going so far as to sleep outside her window in the X-Mansion. That’s because she showed him such kindness when others rejected him, and as their relationship developed, Siryn managed to calm Deadpool down a little and convince him to do some good.
A change in the comic book’s creative team unfortunately meant that their budding romance never got to be fully explored, so it would be extremely satisfying to see the Deadpool sequel take these two characters’ love story and really run with it.