1) Oscar Isaac
So far, these prospective Norman Osborns have not strayed too far from the traditional view of the character. Given how the MCU will give us a younger Spider-Man than before and an, um, unusual version of Aunt May in Marisa Tomei, it is probably more likely that Marvel would do something different with him, as well. Our choice for a left-field Osborn, then, is none other than Oscar Isaac.
[zergpaid]Isaac is one of the most versatile actors working in Hollywood today, with recent roles including a dodgy billionaire in Ex Machina and the dashing Poe Dameron in The Force Awakens. He could easily stretch himself to play a crooked fat cat like Osborn. Plus, he needs another part in a Marvel movie that actually utilizes his talents, unlike his wasted turn as the titular villain in X-Men: Apocalypse.