9) Cindy Moon/Silk
A relatively new character, Cindy Moon was bitten by the same radioactive spider which bit Peter Parker. However, he never knew about this as Cindy was hidden away by a mysterious man known as Ezekiel Sims (more on him later) after her powers emerged, and she spent years locked away from the world. That was to stop a vampiric like being known as Morlun from tracking her down, and some time after Spidey defeated him, she was finally freed.
It was then that Cindy became Silk, embarking an a relationship of sorts with Peter (their connection through that spider means they find each other overwhelmingly attractive, something which would be best left out of a movie). While the decision to have another person bitten by that same spider was controversial with fans, Cindy is a great character and having her somehow involved in this new series – as a fellow student? – opens the door to many new stories and perhaps even a spinoff.