The Gnucci Family
Though Frank is trying to lay low while working at a construction site, it just so happens that a few of his co-workers are mixed up with some dangerous mobsters. To get their own money back, a group of them decide to hit up their poker game and steal their cash. Obviously, it goes wrong, and Frank takes it upon himself to wipe out both the mobsters and his crooked co-workers.
The mobsters are mentioned to be the Gnucci family, which is another name that will ring a bell for comic fans. In the source material, the Gnucci crime family is run by Isabella Carmela Magdalena Gnucci, commonly known as Ma Gnucci. Ma was said to be the most powerful woman in New York City, with both the mayor and the police commissioner wrapped around her finger.
However, as he likes to do, the Punisher took out most of her men and fed her to some polar bears at the zoo. Somehow, Ma managed to survive, albeit at the cost of all four limbs. Descending into insanity, Ma swore a vendetta against Frank, hiring the heavyweight hitman the Russian to take him out.